Carbohydrate Binding Modules
Stability and Ligand Promiscuity of Type A Carbohydrate-binding Modules Are Illustrated by the Structure of Spirochaeta thermophila St CBM64C
A CBMs play a critical role in cellulose recycling, their mechanism of action remains poorly understood. Here we produced a library of recombinant CBMs representative of the known diversity of type A modules.
The enzymatic degradation of plant cell walls is an important biological process of increasing environmental and industrial significance. Xylan, a major component of the plant cell wall, consists of a backbone of β-1,4-xylose (Xylp) units that are often decorated with arabinofuranose (Araf) side chains.
The breakdown of plant cell wall (PCW) glycans is an important biological and industrial process. Noncatalytic carbohydrate binding modules (CBMs) fulfill a critical targeting function in PCW depolymerization.
The CBMomes of cellulolytic bacteria colonizing different ecological niches present distinct carbohydrate specificities
The energetic constraints posed by anaerobic ecosystems lead to the evolution of remarkable highly efficient supramolecular multi-enzyme complexes of Carbohydrate Active enZymes (CAZymes), termed Cellulosomes (