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SKU
AE00071

Glutaminase

Storage Conditions:
2 °C to 8 °C
Escherichia coli glutaminase (EC 3.5.1.2) is an amidohydrolase enzyme which generates glutamate from glutamine.
Availability
On Demand
Unit Size
2500 U
€169.00
Glutaminase (EC 3.5.1.2) is purified from a recombinant E. coli strain. Glutaminase is an amidohydrolase enzyme which generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Importantly, glutaminase is found in glial cells. Glutaminase is expressed in periportal hepatocytes, where it generates NH3 (ammonia) for urea synthesis, as does glutamate dehydrogenase. Glutaminase is also expressed in the epithelial cells of the renal tubules, where the produced ammonia is excreted as ammonium ions. This excretion of ammonium ions is an important mechanism of renal acid-base regulation. During an acidosis, glutaminase is induced in the kidney, which leads to an increase in the amount of ammonium ions excreted. The enzyme is provided in 2.5 M lithium sulphate.

Activity: 2500 U/ml

Temperature and pH optimum/stability: The optimum pH and temperature are 4.9 and 37°C, respectively.
More Information
Shipping Conditions Room Temperature
Storage Conditions 2 °C to 8 °C
Features >95% pure (SDS-PAGE)
More Information
Shipping Conditions Room Temperature
Storage Conditions 2 °C to 8 °C
Features >95% pure (SDS-PAGE)

MSDS

Material Safety Data Sheets

CoA

Certificate of Analysis

Please insert your lot number to get the available CoA

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