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β-Acetylglucosaminidase 18A, Streptococcus pyogenes
β-Acetylglucosaminidase 18A (SpAcp18A), assigned the E.C. number 3.2.1.96, is a derivative of Streptococcus pyogenes. It is an enzyme that specifically hydrolyzes the 1,4-β-di-N-acetylchitobiose core glycan on immunoglobulin G (IgG) antibodies and other glycoproteins. The recombinant SpAcp18A, purified from Escherichia coli, is a single-domain Glycoside Hydrolase family 18 (GH18) enzyme (see more details at www.cazy.org).
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Produced On Demand
β-Acetylglucosaminidase 18A (SpAcp18A), assigned the E.C. number 3.2.1.96, is a derivative of Streptococcus pyogenes. It is an enzyme that specifically hydrolyzes the 1,4-β-di-N-acetylchitobiose core glycan on immunoglobulin G (IgG) antibodies and other glycoproteins. The recombinant SpAcp18A, purified from Escherichia coli, is a single-domain Glycoside Hydrolase family 18 (GH18) enzyme (see more details at www.cazy.org).The protein is supplied in a solution containing 35 mM NaHepes buffer (pH 7.5), 750 mM NaCl, 200 mM Imidazole, 3.5 mM CaCl2, and 25% (v/v) glycerol, at a concentration of 0,5 mg/mL. Bulk quantities of this product can be made available upon request. To place an order, simply visit our website. We offer fast and secure shipping worldwide.
| Shipping Conditions | Shipping: Dry Ice to RT |
|---|---|
| Storage Conditions | -30°C to -15°C |
| Class | Glycoside Hydrolase |
| Activity | Acetylglucosaminidases |
| Family | GH18 |
| EC number | 3.2.1.96 |
| Organism | Streptococcus pyogenes |
| Architecture | GH18 |
| Optimal pH | 7.4 |
| Optimal Temperature | 25°C |
| Substrates | β-1,4-di-N-acetylchitobiose on immunoglobulin G (IgG) antibodies |
Collin and Olsén. (2001) EMBO J. 20(12): 3046–3055.
Collin and Olsén. (2001b) Infect Immun. 69(11):7187-9.
Collin et al. (2002) Infect Immun. 70(12):6646-51.
Sjögren et al. (2011) BMC Microbiol. 11:120.
Trastoy et al. (2013) Acta Crystallogr Sect F Struct Biol Cryst Commun. 69(Pt 12):1405-10.
Trastoy et al. (2014) Proc Natl Acad Sci U S A. 111(18):6714-9.
Trastoy et al. (2018) Nat Commun. 9(1):1874.
Collin and Olsén. (2001b) Infect Immun. 69(11):7187-9.
Collin et al. (2002) Infect Immun. 70(12):6646-51.
Sjögren et al. (2011) BMC Microbiol. 11:120.
Trastoy et al. (2013) Acta Crystallogr Sect F Struct Biol Cryst Commun. 69(Pt 12):1405-10.
Trastoy et al. (2014) Proc Natl Acad Sci U S A. 111(18):6714-9.
Trastoy et al. (2018) Nat Commun. 9(1):1874.
| Shipping Conditions | Shipping: Dry Ice to RT |
|---|---|
| Storage Conditions | -30°C to -15°C |
| Class | Glycoside Hydrolase |
| Activity | Acetylglucosaminidases |
| Family | GH18 |
| EC number | 3.2.1.96 |
| Organism | Streptococcus pyogenes |
| Architecture | GH18 |
| Optimal pH | 7.4 |
| Optimal Temperature | 25°C |
| Substrates | β-1,4-di-N-acetylchitobiose on immunoglobulin G (IgG) antibodies |
| Shipping Conditions | Shipping: Dry Ice to RT |
|---|---|
| Storage Conditions | -30°C to -15°C |
| Class | Glycoside Hydrolase |
| Activity | Acetylglucosaminidases |
| Family | GH18 |
| EC number | 3.2.1.96 |
| Organism | Streptococcus pyogenes |
| Architecture | GH18 |
| Optimal pH | 7.4 |
| Optimal Temperature | 25°C |
| Substrates | β-1,4-di-N-acetylchitobiose on immunoglobulin G (IgG) antibodies |
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Certificate of Analysis
