Chloramphenicol (MB02402)


25 g


Description: Chloramphenicol is a synthetic broad spectrum antibiotic against gram-positive and gram-negative bacteria. It is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol resistance genes. Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step by binding to the 50S ribosomal subunit and preventing attachment of aminoacyl tRNA to the ribosome. It also inhibits mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription.

Chemical formula: C11H12Cl2N2O5

MW: 323.1

CAS number: 56-75-7

Soluble in: Water (slightly), methanol and ethanol

Storage: stable at room temperature; to increase shelf-life, store at 2-8 ºC

Certificate of Analysis ZN112
Certificate of Analysis YO041
Certificate of Analysis YO021

A Combinatorial Approach to Optimize the Production of Curcuminoids From Tyrosine in Escherichia coli
Rodrigues JL, Gomes D, Rodrigues LR
Front Bioeng Biotechnol, 2020

Interaction studies between periplasmic cytochromes provide insights into extracellular electron transfer pathways of Geobacter sulfurreducens
Fernandes AP, Nunes TC, Paquete CM, Salgueiro CA
Biochem J, 2017